I thought I'd share this as a frequent topic on these forums is the question of self-publication. Since amazon can be a very large part of a self-published author's publication plan, I found this debate interesting.
The debate was held on NPR's Intelligence Squared, which does a very good job of presenting both sides of an issue. While I won't discuss the podcast for fear of presenting a bias, the discussion does broach on a number of topics that I found incredibly enlightening: whether e-books promote quantity over quality, how self-publishing affects both the reader and the writer, and the concept of Amazon's influence over book promotion are just a few of the topics broached.
I encourage anyone thinking about self-publishing to listen: